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HIFU Research

Here are some excerpts from medical journals relating to cosmetic HIFU, as well as links to the full articles.

Article Title: High-Intensity Focused Ultrasound for the Treatment of Wrinkles and Skin Laxity in Seven Different Facial Areas

Source: U.S. National Institutes of Health’s National Library of Medicine

Publication Date: 7th December 2015

Full Article: Available Here

“All seven areas showed clinical improvement at 3 and 6 months compared with baseline.”

“subjective satisfaction was sustained for at least 6 months”

“HIFU could be a safe, effective, and non-invasive procedure that can be used to improve facial wrinkles and skin laxity in Asian skin. It is particularly effective for clinical improvement in the jawline, cheek, and perioral areas.”

“The jawline, cheek, and perioral areas were the sites where HIFU was most effective”

“The adverse effects included erythema and swelling in six cases, and purpura and bruising in two cases. However, the adverse effects were mild and transient.”

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Article Title: Noninvasive skin tightening: focus on new ultrasound techniques

Source: U.S. National Institutes of Health’s National Library of Medicine

Publication Date: 5th February 2015

Full Article: Available Here

“The action of HIFU involves thermal as well as cavitation to cause cell disruption and cell death. The injury that occurs when HIFU is applied to living tissue is the result of a thermomechanical process.”

“Tightening and lifting of sagging facial and neck skin and improvements in the appearance of wrinkles can be achieved by targeting the facial SMAS and platysma.”

“The application of heat at these discrete thermal coagulation points causes collagen fibers in the facial planes such as the superficial musculoaponeurotic system and platysma, as well as the deep reticular dermis, to become denatured, contracting and stimulating de novo collagen.”

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Article Title: Reduction of abdominal skin laxity in women postvaginal delivery using the synergistic emission of radiofrequency and targeted pressure energies

Source: Wiley Online Library

Publication Date: 26 August 2018

Full Article: Available Here

“the investigated device can significantly reduce signs of early postpartum laxity in abdominal area. As such, it is a promising alternative to surgical procedures.”

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Article Title: Efficacy and safety of non‐invasive body tightening with high‐intensity focused ultrasound (HIFU)

Source: Wiley Online Library

Publication Date: 22 May 2017

Full Article: Available Here

“Skin elasticity measured via a Cutometer was significantly improved 12 weeks after treatment at all treated sites “

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Article Title: Efficacy and safety of non‐invasive body tightening with high‐intensity focused ultrasound (HIFU)

Source: Rejuvenation of Aging Lower Eyelids: A Pivotal Clinical Trial

Publication Date: August, 2014

Full Article: Available Here

“true noninvasive rejuvenation of palpebral bags can be achieved, and this method could replace more invasive surgical procedures such as lower blepharoplasty. “

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